An artificial version of a compound in broccoli could hold the key to treating arthritis, say researchers.
The broccoli chemical sulforaphane is known to block the inflammation and damage to cartilage associated with the condition. But patients would have to eat several pounds of the vegetable every day to derive any significant benefit. Sulforaphane in its natural form is also too unstable to turn into a medicine.
But UK drug company Evgen Pharma has developed a stable synthetic version of the chemical that offers the potential of a pill treatment.
A single dose of the drug, known as Sulforadex or SFX-01, is the equivalent of eating 5.5lb of broccoli in one day. In tests on mice affected by osteoarthritis, Sulforadex significantly improved bone architecture, gait balance and movement.
Professor Andrew Pitsillides, who co-led the research at the Royal Veterinary College in London, said: ‘These initial results are very positive for such an experiment and we have convinced ourselves that sulforaphane is a promising agent for the treatment of osteoarthritis.'
Source - Daily Mail